Award Winner

Power Infusing Concentrate,



Power Infusing Concentrate

This is Ultimune, our #1 serum.* It combines all of Shiseido’s advanced research and... innovation so that you can have the best version of your skin as quickly as possible. In just 1 week, Ultimune delivers 28% stronger skin. Your results? Skin that’s hydrated, smooth, firm, and protected from daily damage and ageing.

* Shiseido 2017 full year retail sales
** Inner skin defences index (based on moistureretention rate and transepidermal water loss) improvedby 28% 1 week after application.



Item No. 768614145332




  • 30ml

Add to cart options

Product Actions


Our #1 serum. 1 sold every 9 seconds*. Over 150 beauty awards. 25 years of research.

We developed Ultimune to be used in every context. It works on all skin types and fits into many skincare routines. On its own, Ultimune is a powerful serum. Used as a pre-treatment, it enhances the effects of other serums and moisturisers on top. Our dedication to research and innovation have allowed us to create a product that performs quickly while being easy and pleasurable to apply.

Your results:
96% said it moisturised their skin immediately.

After 4 weeks…
98% said the product was effective overall
97% said it maintained the skin’s supple condition
90% said it improved their skin condition
91% felt it enhances effects of other skincare products they’re using**

*Source: B-NASS sell-in data for Ultimune and Ultimune Eye. Worldwide sell-in, shipped bottles through January to December 2018 (calculated by 24 hours a day)
**Tested by 106 women

Key Ingredients

Key Ingredients

Powerful, Innovative Technology

Ultimune is powered by Shiseido’s ImuGeneration technology. It uses botanical extracts of Reishi Mushroom and Iris Root to continuously fortify skin’s ability to defend itself.

Reishi Mushrooms act as rich antioxidants which are known to hydrate and visibly reduce signs of ageing. Iris root is recognised for its vitality and ability to keep skin moisturised. Together, these ingredients are naturally powerful age defenders for strong, healthy-looking skin.

View all


How To Apply Ultimune

Use every morning and evening after cleansing and before moisturising. When using it with other serums, apply
Ultimune Power Infusing Concentrate first.

  1. Push the pump twice to dispense the formula onto the palm of your hand.
  2. Smooth evenly over a cleansed and softened face.
  3. Massage in circular motions.
  4. Apply moisturiser after. Layer on sunscreen if used during the day.


Power Infusing Concentrate is rated 4.8 out of 5 by 537.
Rated 5 out of 5 by from Soft Radiant Skin! I have very dry skin with fine lines and this product works like charm on my skin! It gives extreme hydration and smoothness to the skin! I It has turned my uneven skin into smooth bright radiant skin! My fine lines are less visible, and my large pores are almost gone! It gives lovely moisturization to the skin and makes it easy to put makeup on! My skin absorbs it nicely without leaving any greasy sheen behind! I use it in the morning and evening after cleansing my skin. The texture is very creamy and absorbs by the skin very nicely. It is power infusing concentrated formula to revitalize and restructure the skin. It has improved the elasticity in my skin and fine lines are fading so I am in love with this product!
Date published: 2020-05-17
Rated 5 out of 5 by from Wonder Serum I have extremely dry skin patches of late on my face and nothing seemed to help put some much needed moisture locked into my skin and then i tried this little beaut of a serum that feels so luxurious going into the skin and sinks into my skin lovely with no tacky or sticky ness like i had trouble with on other serums i have tried. It’s also really helped make my skin look more plump and i’ve definitely noticed a change with my fine lines around my eyes and mouth as they seem less noticeable and gives like a blur effect. Overall i really like this serum and will definitely buying more when my current bottle runs out.
Date published: 2020-05-23
Rated 5 out of 5 by from Ultimate power What a breath of fresh air to get a sample that’s a decent size to try, I mean enough for a few weeks which is exactly what is needed to see if my skin gets on with it and to notice any results, when companies to do this it shows belief in their product, the packaging of this concentrate is so cute and stylish and the product has a luxurious consistency and smells absolutely amazing, my skin felt like I’d had a facial, it melts in and kept hydrated throughout the day, will definitely be buying full size and look forward to trying more from them !
Date published: 2020-05-21
Rated 3 out of 5 by from Good product Serum, although it does not meet all the manufacturer's promises, I think it is worth trying. It has the form of a not very thick, rather watery, translucent gel with a white color. I would describe its fragrance as floral, feminine, pleasant and really luxurious, although a delicate note of alcohol is perceptible. Regularly used serum visibly smoothes, moisturises and adds radiance to the skin. However, it does not affect the brightening of discolorations or the reduction of imperfections that appear from time to time.
Date published: 2020-05-28
Rated 5 out of 5 by from The moisture I need Initially, I tried this product as a sample and I was hooked! You can immediately feel it on your fingertips that it has a silky moisture to it that you can feel hydrating your skin even hours after you've applied it to your face. I'm so glad that this product coincidentally found me. I had to buy a big bottle once my sample ran out.
Date published: 2020-04-27
Rated 5 out of 5 by from Sample review I got a sample of this serum. Very easy to use it and result are amazing! Skin is looking more younger and more hydrated. No any dryness feeling and less wrinkles and age lines. Highly recommend it!
Date published: 2020-05-28
Rated 5 out of 5 by from Best product ever ❤️ I have really dry skin, because of some allergies I have. I used to have eczema on my eyes and I tried so many products (organic, anti allergic skin products etc). And then I've started using Shiseido products ❤️ Especially this product is my favourite and a "must" on my daily skin care routine! Thank you Shiseido ❤️
Date published: 2020-12-02
Rated 1 out of 5 by from No benefits I bought this and am in my 4th week of using it. I have had no change or benefits in my skin since starting its use. This is such a shame as I live shiseido products and was upsold to this serum from the bioperformance glow serum which I was very happy with. I won't be purchasing this again as I saw none of the benefits of bright and soft skin and improved complexion I have seen with other shiseido products.
Date published: 2020-02-29
  • y_2021, m_4, d_12, h_16
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.14
  • cp_1, bvpage1
  • co_hasreviews, tv_5, tr_532
  • loc_en_GB, sid_768614145332, prod, sort_[SortEntry(order=RELEVANCE, direction=DESCENDING)]
  • clientName_shiseido-uk
  • bvseo_sdk, dw_cartridge, 16.1.1, p_sdk_3.2.0
  • CLOUD, getContent, 10ms
  • reviews, product

Recently Viewed